Just as it sounds.... There will be “Dramatics” specifically in reference to social conflicts, confrontations, controversy, hurt feelings, disagreements, highly charged opinions & reactions, temper tantrums, etc.
Friend: Did you hear Becky is going to be at the party?
Other Chick: Well if she is, then she better be No Drama.
Usually a red flag indicating the speaker will be messing with your mind and expects you to just put up with it.
"By the way, I'm taking my Momma up to the cabin this weekend for some quiet time," said Easy Eddie. "I'll call you when I get back... No-no-no! Don't give me no drama."