locker run Share definition Flag The act of opening a line of lockers, then closing them as you run to the other side. Person A: I got bored in the locker room, so I decided to do a locker run. Person B: Must've been noisy. locker run by ChameleonDragon May 9, 2019 0 0 Get merch Get the locker run mug. Buy Now — $32.95 See more merch