Patricia Highsmith is an American writer, author of the books 'The Price of Salt' (also known as 'Carol') and 'Strangers On The Train'.
She was the unusual person and her novels are extraordinary because of deep psychological analysis of human's mind.
Marilyn: Hey, George, have you read the biography of Patricia Highsmith?
George: Uh, don't bother me. You know, I'm watchin' TV.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.