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1. The way to say oprah backwards when you're with friends who are embarrassed to watch it.

2. a painful little pimple in your ear
1. i watched harpo last night in my room with the door closed because i didn't want my brother to hear me, he would have made fun of me so bad.

2. i went to go scratch my ear last night and i found this huge harpo, i thought i was going to die
Harpo by Courtdizzleeee April 15, 2008
Oprah backwards.

Was used in the Dane Cook skit "Pedophiles" on his Rough Around the Edges CD.
"Oprah, it's fascinating. Harpo, she really entertains me."
harpo by YUUUP January 26, 2008
A cute critter that likes to sniff...
Your a Harpo because you sniff it!
Harpo by Night Wolf26 March 20, 2019
Oprah is harpo, harpo is oprah.
harpo by Blair January 14, 2005
phyco freak who thinks he has friends
he thinks the piano chair is hes frined.. but i still love him!
harpo by sahh November 20, 2003
Harpo is Oprah Winfrey's production company (for obvious reasons)
Harpo and Langley are production companies. Roseanne, Oprah, Cops.
Harpo by Bryn Benn April 16, 2020