1. A derogatory term for a homosexual man.

2. Someone who is completely insane.

3. A cake made with bits of fruit and drenched in scotch.
1. Uncle Jim married Pete? I didn't know he was a fruitcake!

2. Uncle Jim married a blender? I didn't know he was a fruitcake!

3. Me: What's a fruitcake?
Someone Else: It's a cake made with bits of fruit and drenched in scotch.
Me: Drenched in scotch? Sounds like my Uncle Jim.
by InfrequentNinja February 10, 2004
A person who is insane, nuts, loopy
Brian Tamaki is a fruitcake
by Pol Pothead December 30, 2011
a fruitcake is someone that is either homosexual or acts oddly on a daily basis
Nick, you are a fruitcake. You jump around all day like a tard.
by Ian Gamble September 19, 2005
Sarah Palin is a total fruitcake—and so are the idiots who buy her book.
by T. Boondoggle Blivet December 20, 2009
1. n a dessert; a rich cake consisting of dried fruit and nuts

2. n a homosexual man, or one who seems to be
"My mother received yet another fruitcake from her cheap coworkers as a Christmas present."

"Look at that guy with his flip-flops and unusually primped hair. What a fruitcake!"
by Vee April 22, 2004
An affectionate nickname for former Mayor of New York City, Rudolph Giuliani.
There's only one fruitcake on that stage.
by MagicMystile January 10, 2008