In the game VR chat you travel to a certain Island (named the Ugandian knuckles island)where you find a deformed shorter creepier version of knuckles (from sonic) that you are able to equip as a skin. Any player visiting the island will be visited by a crowd of the Ugandian knuckles (players)screaming the odd phrase "Do You Wanna know de way" mockin the Ugandian accent.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.
You didn't get any napkins with your takeout pork fried rice? Womp womp.