cream-of-tuna Share definition Flag Cream of tuna is period sex. When the guy ejaculates into the girl on her period, he creates cream of tuna. “We totally did a cream-of-tuna last week!” cream-of-tuna by Jonesies Locker June 13, 2018 0 0 Get merch Get the cream-of-tuna mug. Buy Now — $32.95 See more merch