cheer it up Share definition Flag To cheer loudly and with great enthusiasm. To drive oneself into a frenzy from cheering. I totally cheered it up when the Celtics won.Did you see Liz cheer it up at the show last night? cheer it up by Mathy Cathie February 19, 2011 0 0 Get merch Get the cheer it up mug. Buy Now — $32.95 See more merch