Yotsuba 

The Fourth Nakano sister from the anime called Quintessential Quintuplets. She's definitely the best girl and she loves smiling always.

Yotsuba really deserves as a bride

Yotsuba by NotYotsuba October 21, 2021

Yotsuba&! 

The newest creation from that zany-minded Kiyohiko Azuma, creator of Azumanga Daioh.
The main character of his new manga is a girl named Yotsuba, similar to Chiyo-Chan, but with green hair and four pigtails. And co-incidentally, Yotsuba means four leaves.

The newest creation of Kiyohiko Azuma is Yotsuba&!

Yotsuba&! by ChIyO-ChAn August 3, 2005

Yotsubro 

Yotsubro, deriving from the latin term, Yotsubus, meaning all knowing chad, is a term to describe the high intellect humans that live on this planet. They are well known for using their high intellect to discover and understand many truths unbeknown to any human being of an IQ sub-300, most famously the answer to life itself, and that the character Yotsuba is the best girl in Quintessential Quintuplets. Staying near these almost God-like beings for long periods of time is not recommended, as their high intellect may melt regular brains.

"Dude that Yotsubro over there is so smart, they just decked that ninonce using their words"

Yotsubro by yotsubro February 13, 2020

Yotsuya 

A person with big energy. She loves and cares about her relatives so much, she's cute yet she doesn't know. Might be a quiet but sweet girl, but once u get to know her and she trusts u enough you’ll realize she’s funny and quite immature.

I wish I had Yotsuya in my life.

Yotsuya by Yumaru November 25, 2021