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Rob Lowe 

To get blackout drunk, do a pile of cocaine, fornicate with a hooker, and then pass out face down.
"I had such a terrible week at work, I'm going to Rob Lowe tonight!"
Rob Lowe by The Fat Jew April 24, 2006

Rob Lowe 

A brilliant actor (not for his acting or sexual advances, for his criminal escapades).
"I bashed that fuck, but the cops rolled up and I was busted down like Rob Lowe."
Rob Lowe by Diego June 23, 2003

Rob Lowe 

1) the gay actor.

2) that's it. it's not slang for a bloody blow job or anything. geez.
Rob Lowe is in the television show, "The West Wing. He's so gay."
Rob Lowe by seanie shizzle December 18, 2005

Rob Lowe 

1. See gay
2. An ex gay porn star.
3. Gay
4. Someone that did gay porn
Rob Lowe by guy wearing black January 8, 2004
The hottest, sexiest, most goonable actor that has ever lived
Even in his 60s, I'd goon to Rob Lowe!
Rob Lowe by RobLowesBum February 4, 2026

The Rob Lowe Effect 

When you notice someone notice something.
The Rob Lowe Effect: While watching a meteor shower and seeing a big meteor, I noticed Jake was looking in the same direction and made an excited expression. I noticed Jake Noticing the Meteor. i.e. I noticed someone notice something.