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RS is an abbreviation for Real Shit. It's a common saying when gangsters talk, or when some of us pretentious fags feel like a hood rat.
TJ: ayyy nigga! you got dat good shit bruh?
RayRay: yea my main man! RS bruh. real shit.

Tyler: Hey boss, did you get that Q3 sales report?
Richard: Yes I did. RS, expect a promotion in a few weeks.
by Seishaaa February 13, 2011
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An abbreiviation for an MMORPG called runescape . A Very cool game.
What's your RS Combat Level?
by Inquisitor911 February 14, 2005
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Abbreviation for Relationship. when ur a lazy Bitch who dnt like spelling words longer than five letters.
i don't feel like Spelling" Relationship " so I am going to Abbreviate it with "Rs".
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Abberviation for RuneScape, the massive online Java-based gamed by Jagex. It is not gay.. its cool.
bob:im getting rs today when will you be on?

jane:probably tomorrow
by bobie November 18, 2004
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An abbreviation for "Rape Suspect" used in Police terms to desribe the events in a crime scene.

In everday use, an RS would be someone that looks suspicious, untrustworthy, or a bit sketchy . Or it could be someone that sneakily follows people (thus making them RVs of the RS).

See also: RV
"Look at the RS following those kids"

"I smell an RS"
by Maloon April 30, 2006
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If you searched for these 2 letters then you're more then likely looking for definitions of runescape.
Well, here you go.

1. RS-ing - the act of playing runescape
2. abbreviation to refer to runescape
I was playing RS all night the other day, and i realised...I've wasted my life following this gay ass game.
by Betterman February 25, 2005
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