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1. When you stand to make a lot of money from a bet or business venture.

2. When your the likelihood of scoring with a particular woman is exceptionally high.
1. Bill was quids in from his bet at the races

2. "Mate, did you see the way that girl with the massive rack was looking at me? I'm quids in tonight"
by Richard "Docking" Brown November 01, 2009
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