perma-fried

to be permanently effected by drugs, even after not taking them for a while.

i don't think weed or acid permafry people, but cocaine will change someone for life.

by minghi May 22, 2003

perma-fried

v 1. to appear as if on drugs, even though one is sober.

"Wow that Mark Fry kid is perma-fried."

by MF September 06, 2002

perma-fried

which the user of the drug (mainly LSD) feels some effects of the drug (example; sever memory loss) for a vary long time after use of the drug year possibly longer ( the conduction will get better over time but user may never feel quite the same)

by cody ( just did big @$$ report on lsd) May 29, 2003

Perma-Fried

To have done so many drugs, that one would expect you to be affected by drugs 24/7, even though you might not be, but you probably are.

James: Alex are you high?
Alex: Dude i dont even know i have done it like four times today already.
James: you must be perma-fried

by Free Weezy June 08, 2010