Penilemice Share definition Flag Penilemice are small creatures that bury into your penis and make it erect as they eat it from the inside, the only way to get rid of them however is to buy cats. "Oh no! I have Penilemice in me!" "Dude you better buy some cats quickly!" Penilemice by The Mad Penilemouse April 23, 2017 Get the Penilemice mug.