Pain in the ane Share definition Flag Phrased used in place of "pain in the ass". "Ane" is short for anus. Plus, it rhymes. So that's good. My dog won't stop chewing the couch. He's being a real pain in the ane. Pain in the ane by AssHull10 February 28, 2011 0 0 Get merch Get the Pain in the ane mug. Buy Now — $32.95 See more merch
