Oop-de-oop Share definition Flag A five receiver set used for American Football, made famous by the movie Varsity Blues. If the Patriots traded for Terrell Owens, they'd have to run the Oop-de-oop to accommodate all their talent. Oop-de-oop by J_Z December 10, 2007 0 0 Get merch Get the Oop-de-oop mug. Buy Now — $32.95 See more merch