Nyaff is a word used mainly in the West of Scotland; especially around the Glasgow area that is used when referring to someone who is a bit weird or 'off' or just to refer to someone who you don't like in general.
by ScotchMick August 07, 2015
as used in Scotland. "a wee nyaff" a very irritating person. When they come into a room, you want to leave.
by Anonymous November 04, 2003