N.E.S.

Not enough sex syndrome. Terrible condition that occurs in people who do not have enough sexual intercourse. This condition causes the genitals to shrivel up and gather dust.

Nick: Why have my balls shrunk to the size of prunes.
Cody: You have N.E.S. because you have never had sex.

by Infamoustoaster November 15, 2009

N.E.S

Not Enough Sleep found most commonly in teen males.

Yo, Kevin had some bad n.e.s. this morning but it wore off when I fucked Bridget in the ass.

by J.D.. November 8, 2006