Knuckle Up

To prepare to kick another's ass, getting prepared to engage in fisticuffs

If you get up in my grille, you best knuckle up, motherfucker

by stefanali pops September 26, 2005

knuckle up

a phrase uttered in encouragement meaning: "muster your courage, intestinal fortitude and love for the American-way in preparation for an upcoming (or admist a) challenge
of epic proportions!"
(uttered many times by one of the dudes in the movie "The Matrixs:Revolutions" during battle
against the electro-mechanical foe)

"Here they come boys ... Knuckle up!"

by abc July 13, 2004

knuckle up

to prepare to fight.

Guy 1 "i was at the bar chillin talkin to this girl after the band played, then this dude looked at me like he wanted a problem."

Guy 2 "what happened?"

Guy 1 "I had to knuckle up then his boy pulled him back."

by J Fri May 11, 2008

knuckle up

TO Put Up YOUR Setz And get ready to fight

Knuckle up nucker

by shane June 18, 2003

Knuckle Up

The Act Of Whupping Someone's Ass!

BITCH All In My FACE We Bout 2 KNUCKLE UP In Did Bitch!!!

by MS. BOUNCE DAT AZZ July 12, 2006

Knuckle up

To masturbate
The act of masturbation

Guy 1: Did you see Stacey?

Guy 2: Yeah, total nipple slip! I'm totally going to knuckle up to that later

by leobaby1 November 18, 2011

Knuckle Up

When two men choose to engage in mutual masturbation, implementing a "thumb war" grip and jerking themselves off simultaneously, locked at the knuckles.

Since he had a girlfriend, the young man decided to knuckle up with a buddy.

by DaXymbiont February 7, 2018