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A fight or other violent skirmish between at least two punters. Often alcohol related or occurs in a pub. To 'go the knuckle' is to punch on.
Dude 1: Did you see Johnny Carter in that biffo the other night?

Dude 2: Yeah, trust Johnny to go the knuckle.
knuckle by 1257 April 23, 2013
A slang term for male genitalia; derived from moose knuckle.
Henry discovered that he had an unusual growth on his knuckle.

That bathing suit is too tight! I can totally see your knuckle. It's a knuckle hugger.

She grabbed his knuckle and held tight. He gasped.
Knuckle by infiric December 16, 2008
to give five with the back of the hand;
You got that bitch up the ass..give me some knuckle on that one.
knuckle by Anonymous August 5, 2003
Any friend that assists you in your endeavors, or that you assist in theirs. A knuckle is of equal standing and not be confused with a minion, even though they may let you take the lead in situations where they are assisting you, just as you let them take the lead when you are assisting them.
Some of my knuckles came over last night and we gave the car a tune up and put in new speakers.

I burned my songs onto a mix cd for one of my knuckles.

One of my knuckles found a generator for next weekend.
knuckle by squegie September 20, 2005
a precise point on ones finger made efficient for causing maximum damage
male b: im so mad at your mom, she knuckled down my house last night!

male j: we have the same mom! knuckle head!!
Knuckle by jordan sollinger January 13, 2008
4 grams of a substance, preferably cannabis
Let me a knuckle of that Chemdawg
Knuckle by speedcore909 September 8, 2017