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Inbreeding depression 

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1.) The lowered overall fitness of a population due to reproduction between closely related individuals, thereby lowering heterozygosity in the population and allowing deleterious alleles to be expressed.

2.) The crushing guilt that follows fucking your sister.
Inbreeding depression is a serious risk in small populations.
Inbreeding depression by SimpHawk September 20, 2018
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Related Words
Inbreeding depression • inbreeding • CORPORATE INBREEDING • Genetic Inbreeding • psychological inbreeding • social inbreeding • product of inbreeding • Inbreading • Increeping • Inreading
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