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A sarcastic and cynical way of responding to something that was originally intended to be humorous. It is often best used when targeting a single person with a large group of friends backing you.
Zack: Dude, what if I had a really HOT girlfriend?

Adam: Dude, you know what would be even better? A MILLION dollars! HOHOHO!

Riley: HOHOHOHOHOHOHOHOHOHOHOHOHOHOHOHO
Hohoho by TheCaptainsCrew July 24, 2011
Something Santa says when he sees your wife, daughter, and sister in the same room.
Santa: Hohoho! DAMN you're girls are fine
Hohoho by me=beast March 17, 2010
n. One who becomes promiscuous on an annual basis at the office Christmas party.
Dude 1: Gonna get lucky at the office Christmas party?

Dude 2: Dunno, who's gonna be there?

Dude 1: HOHOHO
hohoho by D'emon March 20, 2003
if someone say hohoho u gotta answer with ur mom is a hoe. Its just a word of mass distraction that can destroy friendships aswell as ur face.
Dude.1: HoHoHO
Dude.2: Ur mom is a hoe
Dude.2: Breaks his fucking face and his nose
hohoho by TehKilla November 16, 2020
HOHOHO is Santa's HOHOHO witch means Mrs. Clause when he fucks Mrs. Clause he yells your my HOHOHO just a jolly old HOHOHO big fat hohoho
What does Santa say to Mrs. Clause?
when he fucks her he says your my big fat HOHOHO
HOHOHO by dustybusty September 24, 2021
Please don't say Hohoho!!!
Hohoho by sus,,.. December 7, 2025