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Highest In The Room 

A song by Houston rapper, Travis Scott. First teased in a Kylie Cosmetics advertisement. Production includes Mike Dean, OZ and Nik D. The song describes Travis in his most intoxicated state. After months of waiting the song was released on October 4, 2019.
Me: *Playing Highest In The Room*
Dad: Are you listening to Highest In The Room?
Me: Yeah
Dad: Turn it off
Me: Why?
Dad: We have bigger speakers downstairs
Highest In The Room by XXXCUMINMYASS December 31, 2019

highest rated comment 

comments that have the highest number of thumb ups from youtube users. usually, these comments include saying something stupid/irrelevant about the number of 'dislikes' or justin bieber

most of the highest rated comments are also some of the most dumbest.
i'm fking tired of highest rated comments.
highest rated comment by wowspare September 16, 2010

Highest Pistivity 

1. When you're extremely, extremely pissed off.

2. When you feel like you want to crush flowers.

3. When you're so angry you feel like strangling your cat, but can't because it's so cute.
Saying "I'm pissed off to the highest pistivity there is." when your boyfriend did something like get drunk with another girl.
Highest Pistivity by CAKB September 26, 2009

highest pitch of voice 

The highest attainable frequence of a spoken voice.
That dude from that party posessed the highest pitch of voice! Blood came out my nose!
highest pitch of voice by Ellis August 21, 2004

highest of keys 

Drawled out version of high key Most commonly used when desiring to describe something with specificity or disputing lowkey
Don: "Ay bro, but on the Highest of Keys, she's a hoe"
Bro: "Yeah I know, but I'd still lowkey hit."
-----------------------------------------
Bonnie: "Lowkey, Tyrone is bomb af."

Jas: "No, on the Highest of Keys he is!"
*Fits of Laughter*
highest of keys by Bullshitter101 December 31, 2014

Highest Common Denominator 

A discrete reference in the homosexual community for a homosexual ("common") male that is both a pitcher ("highest") and a catcher ("denominator").

Such terminology is necessary so that homosexual males can easily and discretely identify themselves to other homosexuals as a top, bottom, or both.
He identified himself as a Highest Common Denominator on his online dating profile to broaden the pool of potential homosexual partners.