Gregodenitis Share definition Flag An affliction affecting young men with faces that make them look older than their actual age; i.e. Greg Oden. Damn that nigga ugly, he got him a bad case of Gregodenitis. Gregodenitis by craig&jevon October 19, 2009 0 0 Get merch Get the Gregodenitis mug. Buy Now — $32.95 See more merch