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1. Total unfairness.
2. When the man just brings you down for no god damn reason.
3. An act of bad taste, when someone does something ghetto or rips you off in a bad away.
1. Leroy: So, you're sayin that you failed me cause I'm black? That's grimes.

2. Steve: God damn, I just got shit on by a bird, good luck my ass. Life is just grimes.

3.Leroy: Ayo Steve!
Steve: Yeah?
Leroy: Did you steal my newspaper off of my front porch again?
Steve: Well...uhh..you see.......aw damn come on man i'm not trying to pay 75 cents for this shit
Leroy: Damn man that's grimes.
grimes by SystemF December 24, 2006
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Bev got pissed at his girl, so he gave her the grimes.
grimes by trip_es March 31, 2008
The way cool people say grimy, which is also a sweet word.
*Steps in Dog Shit and Looks at It*
Lacey: Grimes!!!

Minas: Joe got herpes
Anna: That kid is grimes McGee
Grimes by BrooklineMA March 22, 2009
Man, that dude is a total grimes!
grimes by AaronG9 June 24, 2006
a nasty dirty girl who had sex with a lot of guys
Marlin: Hey do you think bertha is hot? Should i get with her?

Steve: Hell no dawg, shes grimes!
grimes by estevan17 October 30, 2008
An epileptic stanky whore, who is essentially grimey.
Friend 1: You hooked up with Grimes last night?
Friend 2: Yeah so?
Friend 1: Dude that's so nasty, you better check your junk for spots for the next six months.
A lowdown janky asf person who does the most despicable deplorable shit. To do something something so horrible and unethical it's shocking.
He got his girlfriend and her sister plus their cousin pregnant at the same time?

Yo, that Nigga is Grimes!

She tricked two dudes into paying child support and neither one is the father?

Grimes Bitch just Grimes!

Nigga you peed the bed not because you was drunk but just too lazy to get up?

Nigga you Grimes and nasty asf!