To be defeated or beaten on many levels in many facets of life including but not limited to sports, school, and fisticuffs.
The inability to succeed at anything despite enormous effort.
Jane: Last week Bobby spent 24/7 studying for his Biology final and he still failed.
Alex: I know. Even the kid with a 65 IQ topped his score. He has a major case of Foot-In-AssDisease.
This is what will happen if you are an annoying person. It could happen when you act stupid at the bars around drunk people that are twice the size of you.
What usually happens during rainy dayswhen the concrete is wet and the traction on your shoe is reduced. Typically known as a foot slid into the rectum(usually barefoot) and sometimes consists of a 3 hour hospital wait.