A substitute for "excuse me" originating from Wayne's World 1 and 2. In the movies, Wayne will follow with "A baking powder?" in substitute of "beg your pardon."
Fucking annoying amalgamation of 'Squeeze' and 'Excuse me'.
Perhaps used to be cool, when I was about 5, but is now used by timid fat women at work who want you to move, are passive aggressive and go all red in the face before they say it because really they want to hit you in the head with a broken bottle.
Inside Timid Woman's Head:
"This fat fucking cunt I want to finger fuck her whole family"
Outloud in a high-pitched whine:
"Exsqueeze me"
perhaps some more 'e's can be added:
"Exqueeeeeeeeze me"