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"The most interesting, fascinating, wise, quick-thinking, intelligent, prudent, beautiful, hot, sexy, sensual, empathetic, mysterious, warm and consuming person in the entire bloody universe" and people that know her are the luckiest people to ever exist in the same time as her.

Not to be confused with "Anne"
"I met lady En today. She seems so selfless and humble."
"You are very lucky to know her. She is everything !"
En by shootingstar_mss July 10, 2020
A word.
Freddie Mercury said that it's a word while playing Scrabble, so it is a word.
Brian: Fred that's not a word.
Fred: No of course EN is a word!
En by Aiko_Aoyama November 5, 2020
A phrase commonly used on Twitter.com by Troy Farthing and a large percentage of the northern population, who uses it every 4 words. It doesn’t actually have a specific or precise meaning
Person 1: Hero You en
Person 2: Nah you en, god you are en
En by BilboBCFC October 29, 2020
a flop dude. similar to mr. flop
yo en is a flop master.
en by Mike James Bitch September 10, 2006
En is a anger filled, steroid eating, girl pulling machine. He’s caring sometimes but doesn’t that shit from anyone.
You see him when that fight? He must be a En.
En by DGenarous December 4, 2019
EN is an acronym that stands for "Erect Nipples". It is a sensation that can happen to either a man or woman when they are cold or sexually aroused. Often one can spot a bad case of EN from across a room, especially if the person with it also suffers from a case of pancake nipples.
Guy 1: Man, i almost put my eyes out on my girlfriends nips last night
Guy 2: How the hell did that happen?
Guy 1: We were banging on top of the deep freeze and she had a wicked case of EN, i swear they were harder than a diamond in an ice storm!
EN by Kylav January 20, 2008