A condition afflicting certain personality-types wherein everything they do in social situations is just a 'downer'.
My father has Downer Syndrome
by dubbyd November 27, 2017
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The horrible feeling you get when your back home after a holiday to magaluf
John: Dude i feel so depressed since coming home

Doctor Pete : you got Magaluf downer syndrome!
by Milic15 August 1, 2010
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