Women that become so close their menses occur at matching intervals.
Georgio: My wife is so close to her best friend that they've become cycle sisters.

Gordo: Bloody pants says 'I love you real hard.'
by redstripe November 13, 2008
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Used to describe two women who hang out so much that their periods start to sync up.

Also, used to describe women hockey fans in Tampa Bay, who attend games while on their rags, and in between periods thrown their tampons on the ice, just as Detroit redwings fans throw octopuses on the ice (sometimes also called “bloody octapussies”).
Holy shit, our team is losing real bad, better go all cycle sisters To encourage their blood to pump.
by BloodyVag May 11, 2019
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When you’re so close to your girls that your periods sync up. You become cycle sisters.
Bae we both need a tampon because we’re cycle sisters. Love you bae.
by S Cal January 19, 2019
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