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Biggie 101 

A requisite course for earning a degree from Gangsta Academy. Topics include proper stowage and transportation of a firearm (or "piece"), enjoyment of fine Jamaican rums, and conversing (or "spitting game") with females ("bitches", "hoes", or "honeys").
Bitches in the back looking righteous
In a tight dress, i think i might just
Hit her with a little Biggie 101

TRANSLATION:

Some females exquisite in appearance are in the rear of the venue. One of them is wearing a dress that clings rather tightly to her voluptuous feminine form. Perhaps I shall attempt to apply some of the techniques demonstrated by Professor Smalls to this situation!
Biggie 101 by im_wrecked December 18, 2009
Related Words
Russian propaganda posters 101
101 by Petr January 25, 2004
Double vaginal penetration (i.e. two penises simultaneously inserted in to a vagina).

The number 101 is an example of iconicity whereby the number 1 represents a penis and the number 0 represents a vagina.
"I must call up to Limerick there Friday night to do a 101 job"
101 Job by cheesy454 November 17, 2022
An exclamation you make when you realize something you should have known all along, or when the person you're with has a startling revelation about something obvious.
Bob: "Wow! I never knew that donuts were so bad for you!"
Sally: "Duh 101"

Francine: "I should have known he was married! Duh 101!"
Duh 101 by zandwich October 5, 2010

room 101 

The room where the Ministry of Loveinflicts its worst torture - subjecting you to whatever you fear the most, in George Orwell's 1984
"Do anything to me! You've been starving me for weeks. Finish it off and let me die here. Shoot me. Hang me. Sentence me to tenty-five years. Is there somebody else you want me to give away? Just say who it is and I'll tell you anything you want. I don't care who it is or what you do to them. I've got a wife and three children. The biggest of them isn't six years old. You can take the whole lot of them and cut their throats in front of my eyes, and I'll stand by and watch it. But not room 101!"
- the skull-faced man, 1984
room 101 by D. Stern July 29, 2005

life 101 

Things that life taught you, often at your expense.
John : "Hi, Anna, how are you ?"
Anna : "Not so good... This morning I stubbed my toe. Then I spilled coffee on my blouse, I had to change clothes. Of course, I missed my bus and was late for this very important meeting."
John : "Yeah, mornings suck, that's life 101."
life 101 by tatal35 October 11, 2009