It's what fucking douches use in a whole shitload of IM conversations.
Jake: Yo, how's the paint on the roof drying?
John: o.O
Jake: ...
Jake: You douche
by Jake Small September 14, 2007
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creeper96: i havent talked to you ever, but would you like to meet up some time!?!

i_h8_men27: #O.o#
by pastamania92 September 25, 2008
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It means strangeness, weirdness, complete damn abstractness. like the loch ness.
your really weird ~ O.o
by little miss sunshine October 12, 2006
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1. L0LZ NIGGA U DUN ATE MY CHEESE SAMMICH.
2. See cmcand vote thumbs up.
Bill: o.o;;
Ted: o.o;;
by Shawn July 25, 2004
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Wide eyed and scared; panic-stricken; nigga shock.
(a nigga's car breaks down in the third ward)

"this nigga is scared of niggers...u scared, Taniqua?" O.O

"naw D'Andre, I aint scared." O.O
by dr. toofess April 13, 2013
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A surprised, intriuged, or shocked face usually used by roleplayers in chatrooms.
Person 1: Screw you.
Me: o.O;;... Righ'...
by Miko-chan August 19, 2003
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Much Like the ;_; this ,o.o, denotes crying because of something in a chat room.
<D00Der2732> u r teh sux0rz
<whiny_bitch> i am not ,o.o,
by Nismo777 February 17, 2004
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