An affliction of a female's sexual organs, usually involving disease of the most foul kind and resulting in an unsightly mess between the woman's flaps. Can also be used to express horror at the dirtiness of a female who has recently been engaged with in sexual activities. Something that smells like a vagina but not a healthy one.
'Don't do it man, it looks like she's got cunt plague'
'I can't believe my daughter has cunt plague. I smelled it in the toilet'
'Oh Jesus, you stink of cunt plague'
by billybud July 2, 2010
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When a large group of noobs mobs an area with its ineptitude. This can occur in games or real life.
Woah this Noobonic Plague is making our team suck hard...
by Banerik July 28, 2006
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A terrible disease infecting all high school juniors taking Advanced Placement Language/Composition, or commonly known as APLANG/APLANC/AP English. This rendition comes in many forms, such as:

Type A A-Plague: Having so much work from this class mixed with extra-curriculars and other AP classes to the point that you just don't care and can't muster yourself to do homework.

Type B A-Plague: Being able to care for and only for AP Lang.

Type C A-Plague: Turning into a raged demonic zombie who seeks to chase and kill all souls not enrolled in AP Lang.
Example 1:

Samantha: John, may I copy your dialectical journals and rhetorical analysis for AP Language/Comp?

John: No, I have the AP Plague.

Samantha: >.<

Example 2:

Cody: Let's go play football at the park this weekend and go to this concert!
John: No, I have the A-Plague, I have a timed essay monday, a 3,000 word satire essay due, watch recordings of The Colbert Report to analyze, and annotations for the first half of To Kill A Mockingbird. Then, I have to study for my APUSH test and read all the chapters. Then a physics lab report. Then a mountain of Calc homework. Then economics and spanish tests to study for.

Cody: Your a fucking loser dude.

Example 3:

Jamal: John, are you okay?!?!?
John: "proceeds to bite and devour jamal, the non-AP student"
by jewfro_ballin_dude September 6, 2011
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A disease that affects the mind, caused by listening to Rebecca Black too much and becoming a fan of her. Similar to Bieber Fever and usually fatal.
Guy 1: I'm in love with Friday! It's such an awesome song!

Guy 2: oh shit, the black plague has infected him. I suppose there's only one way to save him now *cocks shotgun*
by bobertman April 8, 2011
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The black plague or black death was a disease epidemic that spread throughout Europe in the mid 14th century. This was mostly due to the bubonic plague. The disease traveled through rat flea bites. Symptoms such as headache, fever, and swelling of lymph nodes were common and sometimes bloody sputum. When the plague was over, 1/3 to 1/2 of the European population was killed. Deaths caused riots, harsher persecution of Jews, and religious fanatics that would go about punishing themselves. The result was a major factor in the beginning of the renaissance.
The most deadly plague in human history is the black plague.
by omgbutters August 15, 2011
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An anti vaxxer. These people are normally below the baseline intelligence, and swear by a discredited doctor's faulty research.
Yo, Kaylee is totally Pro-Plague
Yeah, let's just stay away, she has a few weeks left.
by Bre-1 May 3, 2019
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