When you don't particularly enjoy people of African/African American descent, and would like to request that they politely cease being so loud.
Standing in a Walmart checkout aisle, a single man has had enough of the women in front of him's screaming child.

Man: "SHUT UP NIGGER!"
by SlagFromTheEast February 14, 2017
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The best way to win an argument.
Person 1: Did you know that the best way to win an argument is to say "shut up nerd"

Person 2: No it isn't

Person 1: shut up nerd
by TheLionLiar August 29, 2018
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Used to call out someone when they're starting to sound like a crazy conspiracy theorist.
Comes from the classic King Of The Hill show, where Hank Hill would constantly call out his tinfoil hat friend Dale Gribble.
Person 1: "Don't you know the government is listening on everything you say?"

Person 2: "Shut up Dale."
by Anonyfur May 2, 2020
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A response to a question that you don't actually have an answer for.
Person A: If you're not a pedo, why do you have 15 little girls in cages in your basement?

Person B: Because shut up
by MISTER OWNINATOR December 21, 2009
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Danielle: *singing loudly*
Julie: Can you please shut up?
Danielle: *keeps singing*
Julie: Shut up.
Danielle: *keeps singing*
Julie: I'm serious, this is really embarrassing.
Danielle: *keeps singing even louder*
Julie: SHUT THE FUCK UP!!!
Danielle: *shuts the fuck up* :O
by thegirl123 April 8, 2009
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To ignore your significant other when she tries to prevent you from hanging out and drinking with your friends
Joe said he had to shut the dog up when his fiancée tried to tell him to stop hanging with his neighbors drinking in the garage
by JACK CHAIN September 21, 2018
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A quote from the movie Heathers and part of the actual song Big Fun from the musical Heathers. It has nothing to do with TikTok. If you think it's from TikTok or "that one TikTok song" consider yourself educated. Heather Chandler often says it to Heather Duke, and the line is revisited when Veronica yells "SHUT UP HEATHER" at Chandler's spirit. Please refrain from saying "dang dang diggity dang" is from TikTok, it's from Heathers.
Person 1: Shut up Heather!
Person 2: Oh my god, you know Heathers?

Person 1: What do you mean? This is from TikTok.

Person 2: What the fuck? No! It's not from that musical.ly rip-off, it's from an amazing musical!
by ifelloffmychairlaughing November 13, 2019
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