The mean of Fo Shizzle My Nizzle is For sure, my nigger. often used when a Gangster or some sort of black person (or in some rare cases a white person) says it to his friends to make him seem cool or "gangster"
Rick: you sup joe
Joe: nutt'n much you?
Rick: same.... Oh shit its billy i hate that fag...
Billy: Yo Fo shizzle my nizzle dog
The popular term"Fo shizzle my nizzle" is quite oftenly thought of as meaning "for sure my nigga". However, the true definition is, simply, "rub my dick".
(.)(.)
David said to Mandy"Fo shizzle my nizzle",which got him kicked in the Nizzle(if you know what i mean).
Sally said to Bob"Shall I Fo Shizzle My Nizzle?",Which scared Bob quite a lot.