N. When you wake up during the night and your friend is fucking your girlfriend with a tuba and some sour cream.
Wow, last night I awoke to the sound of a tuba and the smell of sour cream, leaned over and saw my girlfriend had both of those in her vagina. My friend Toby just gave my girlfriend the Smoking Cock Gun of Misery and Despair!!!!!
by Twelve Bananas Yes...No May 26, 2009
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Mukuro😨 Ikusaba,👵 the😱 16th 💢💨student,🙎 ♀️🙎 ♀️ lying 🙀hidden💩somewhere 🙈in 👽this😂 school. 😎The🤖 one 🧓they 🧠call 🤧the🤕 ultimate 😳despair.🤪 Watch 😼out😾 for 👾her.
The 16th student is... Mukuro😨 Ikusaba,👵 the😱 16th 💢💨student,🙎 ♀️🙎 ♀️ lying 🙀hidden💩somewhere 🙈in 👽this😂 school. 😎The🤖 one 🧓they 🧠call 🤧the🤕 ultimate 😳despair.🤪 Watch 😼out😾 for 👾her.
by Nag1to Kinnie March 12, 2021
Get the Mukuro😨 Ikusaba,👵 the😱 16th 💢💨student,🙎 ♀️🙎 ♀️ lying 🙀hidden💩somewhere 🙈in 👽this😂 school. 😎The🤖 one 🧓they 🧠call 🤧the🤕 ultimate 😳despair.🤪 Watch 😼out😾 for 👾her. mug.
Bad things keep happening in a life that makes a person experience a spinning wheel of despair. See also pit of despair; well of despair; depression; sissyphos.
First my mom died. Then my gf left me, my father got heart disease, I quit my degree and my dad cheated me out of my mothers will. Although I have had a few prexious good moments, everything seems to come back. And worse than before. It is like I am stick in a wheel of despair.
by UrbanMolb February 14, 2017
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Another name used for a build a bear reject
Makoto: Build a bear reject

Monokuma: I AM NOT IM A YIN YANG DESPAIR PANDA- wait-
by Shuichi Saihara :) July 13, 2021
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When you know that there will be no netflix and chill tonight, only disappointment. So you just watch some show and contemplate on your despair.

See also netflix and sleep, netflix and angry, netflix and sad, and married netflix and chill.
Did you netflix and chill last night?
Of course not, there was only netflix and despair.
by hazelnutbiscotti July 4, 2018
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Bread that brings much despair
Junko: ayo whered my despair bread go

Monokuma: sorry but i was hungry for despair
by January 20, 2021
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