duff

designated ugly fat friend
the more approachable one

you are duff

omg Katey is such a duff in her friend group

by calumhood.com October 24, 2015

duff

as in to bone a chick. to get duffed out

i duffed this sweet dude last nite yeahhh!!!

by gap slammer November 7, 2006

Fletcher Duff

A meme come to life, a Fletcher Duff is someone who personifies a number of memes often found on the internet without necessarily directly correlating with just one.

"Oh, that meme reminds me of something - i just can't put my finger on it"
"That must be a Fletcher Duff!"

by topg43 August 7, 2022

Duff

Duff is a quiet man when you first meet him yet is incredibly observant and always listening. He takes his time in both thoughts and actions, but in the end is always ready to share the very best of himself. Duff is strong yet gentle, firm yet kind and mushy. If you are lucky enough to have a Duff in your life, then you are guaranteed a funny and generous confidante who will be by your side forever.

You know it's going to be a great night, Duff is coming!

by Duckie1970 December 9, 2023

Duff

The shake at the bottom of a bag of drugs, including the seeds and stems in a bag of weed. Commonly used to describe the shake at the bottom of a bag of crystal meth.

Jeff: Hey, let me get a ball of that fire ice. Dan: All I have left is the duff, bro.

by jlthomas110880 November 25, 2020

Duff

A cocktail consisting of equal parts Cynar, Campari, and gin with a splash of soda and an orange twist.

"Hey bartender, I'd like a drink that's neither too sweet not too bitter."
" How about a Duff?"
"Perfect!"

by megadope September 20, 2023

DUFF

A DUFF is a D- Dumb U- Ugly F- Fat F- Friend basically the girl or boy that tries to cockblock you when you are trying to make a move on a girl or a boy

Shut up you fuckin duff

by Kiddericc March 22, 2021