To let go of all restraints or inhibitions especially with respect to physical activities or sports.
If a fan sees that an athlete is holding back or could use some encouragement he might yell out: "Take the leash off Huey!"

My girlfriend is usually pretty restrained in bed, but not last night. She really took the leash off!
by climbert August 24, 2009
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To poo and really relax afterwards
Hey Steve, I just went to take a load off and now I am hungry.
by HandleInUse69 January 3, 2019
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An excuse girlfriends use to ditch you and hook up with other guys
My girlfriend decided to “take the night off” with her ex boyfriend
by Jason 3 October 9, 2019
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To throw up a little bit to make yourself feel better when you’ve been drinking.... prematurely to when one would “pull trig
Oh boy that pregame hit different. I need to take the top off!
by Thiccc nick October 10, 2020
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A girl grinding on a dude while holding her proverbial cowgirl hat in one hand
-so what did you and Daniel do last night?
-all we did was take the hat off
by drdestructo March 14, 2015
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A threat aimed at someone who is touching you in an uncomfortable or aggravating way.
guy 1: Look, just cuz the hottest girl in school dumped you doesn't mean anything. *puts arm around guy 2*

pissed off guy 2: Take it off before I break it off.
by Keith Hutch. September 24, 2007
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