Duff 

A friend nobody really wants to be around but is tolerated and kept around for the purpose of buying alcohol

an example: duff as in a person around just for alcohol

Duff by 203.goon July 25, 2020

duff 

short term for duffer. someone who is stupid.

that guys hot but hes duff asf

duff by weirdahhbitch December 19, 2022

duff 

English word for semen.

Last night I shot my duff right in her eye.

duff by The Strut September 29, 2004

duff 

adjective describing something lame, or stupid; opposite of kuff

Damn that party was soo duff, way too many dudes in there.

duff by kufflos January 15, 2009

Duff 

Verb; meaning to punch or hit.

"Shut up right now, or I'll duff you!"

Duff by AndreaMK December 3, 2006

DUFF 

"Everyone has a DUFF"
Designated Ugly Fat Friend

Call up your DUFF...we can get her/him to drive

DUFF by xsiennax March 10, 2008

Duff 

UK - to be pregnant

She's up the duff

Duff by Sophie96 April 11, 2015