duff

that ONE ugly, unpopular person in a group of popular, or hot people. (DUFF stands for designated ugly fat friend.)
Jack: Wow, she doesn't fit in at all. She must be the duff out of that group.
by turtles.166 June 21, 2015
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duff

"We saw her boyfriend at the bar and had to duff"
by Dan Tucker December 02, 2003
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duff

To duff. (v)

1) An unspecified act, with the ability to surface in the conversation with vague initialization; a general verb replacement, adding emphasis on the action done.

2) The action/s brought upon in the rare situation of a peg-leg and/or amputee impaling another person’s chest at high velocity, generally in the process of a high-altitude attack.
1) a. "Dude, I'm totally going to duff you in the face if you don't shut the fuck up."

b. "Oh yeah? Well I duffed your mom last night."

2) (In the context of 'Rules of Engagement')
"Yeah, I can totally see that little stubby girl duffing him in the chest."
by Jeff Ott October 29, 2005
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duff

The leftover remnants of meth after smoking. Or small crystals of crappy meth that can be found on tables, etc, in a meth user's home.
We opened to basement door and told Jeff's uncle it was time to go. He screamed "Do you want me to do this F*kking Duff, or what!!!!??" while pounding a table.
by StinkyPP July 16, 2008
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duff

Dumb, Ugly, Fat, Fuck.......... every girl has a friend like this.
that girl is friends with that DUFF chick
by Tin973 November 10, 2006
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duff

"designated ugly friend"

an ugly poor girl you use to laugh at. She has such a scummy pathetic life and drives a 2 dollar pos. Her face is ugly too. Her family is fucked in the head and she makes you feel better about yourself. Though you don't have to, she can make anyone feel better about herself since her life is such a piece of shit.
Boyfriend: don't call the duff tonight, she's too psycho to hang out with.

Girl: Don't worry, i won't, i don't hang with her anymore, it ruins me reputation.
by tawns02 November 16, 2008
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duff

A woman pregnant. Also the name of an Irish winger at Chelsea
by Britboylangers May 21, 2004
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