In the duff

When you are horny as fuck

Yo bro are you in the duff right now?

by c0pen September 8, 2020

Up the duff

When a woman is pregnant.

Elise is probably up the duff by now!

by 7bandittt January 21, 2021

Cassandra M. Duff

A shy, Beautiful young girl. This girl has a short temper, and loves to draw and listen to a small selection of music. With a very adventurous imagination, a very polite attitude, and above average intelligence, she is a very fine young woman.

Warning: Easily irritated by short, pushy boys. May cause bodily harm if tampered with.

"Just leave me alone please!"
"Guys are sooo stupid.."

by Someone who cares February 11, 2005

duff

English word for semen.

Last night I shot my duff right in her eye.

by The Strut September 29, 2004

duff

adjective describing something lame, or stupid; opposite of kuff

Damn that party was soo duff, way too many dudes in there.

by kufflos January 15, 2009

Duff

Verb; meaning to punch or hit.

"Shut up right now, or I'll duff you!"

by AndreaMK December 3, 2006

DUFF

"Everyone has a DUFF"
Designated Ugly Fat Friend

Call up your DUFF...we can get her/him to drive

by xsiennax March 10, 2008