Sis

A acronym for "she is self".
Look at her, sis is beautiful. Which means when you speak of Sis, Sis is yourself. It speaks on how you think and feel of yourself. Positive or negative. Talk to her nice 😘
by M. Divine May 05, 2019
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sis

So It Seems
Given photographic evidence it appears that the parties in question where somewhat aloof, or SIS...
(an abbreviation for social media eg. Twitter)
by Asgard December 22, 2016
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Sis

Term used among gay bottoms that have a double meaning of both “sister” and or “sissy” but used with endearment .
Hey sis how was your night

Sis it was long and hard
by LuiLifestyle April 05, 2022
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sis

Used to show James Charleshq yeet language. Expresses love 😌 and hate ❌.
Me: hey boo
Friend: heyyyy *winks*
Me: bihh dont wink at me sis
by sissysnapped January 01, 2019
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Sis

A commonly used word, mostly by females. Referring to a close friend or a shortened version of “sister”. Some could say this is “basic” and “overused” by more than half the internet. Someone who would use this word would probably:
1. Watch Shane Dawson
2. Say “tea”, “love that”, “queen” a lot
3. Make jokes about hating themselves
4. Bring up their depression randomly
5. Get into online fights in random discord servers
6. Wear thrift clothes
7. Have “aesthetic” things
8. Be sensitive
9. Feel the need to drink Starbucks even though they don’t like it
10. Wear adidas and giant hoodies
And the list could go on...
“Hey, sis! How are ya?”
“Omg! Spill the tea, sis.”
“I got some tacossss sisss:D”
Sis, just stop.”
“Sis, you ain’t cool.”
“Hunny, you needa chill, sis...”
“Sis got some issues”
“Finna slap a bish, sis angry>:(“
“Shhh! Sis imma kill you”
by XxcloudyxX February 16, 2019
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Sis

A word used to replace argh when seeing or hearing something disgusting. It can also be used when someone is acting like a bitch or a slut.
Person A: Cow manure is edible and nutritious in India.
Person B: Sis, that's disgusting.

Person A: I had sex with 5 dudes today.
Person B: Sis!
by Thedarklol October 15, 2021
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Sis

Word used by bitchy Twitter Stans in a usually rude context, who think that they are top shit. These Stans are usually female, and tend to overuse words such as Tea and Y’all.
Twitter Stan: Sis..
Me: You know, I’m just about done with your shit, “JunkookFangirl97”.
by MeganTheCreator April 02, 2019
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