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Main Guy

1. In video gaming, an enemy seen at the climax of a particular section of the game. Also known as a boss.

2. In film, the lead actor.
Friend "Hey wow you finally beat that level!"

You "No I still have to fight the main guy!"

Friend "Hey, who was the main guy in True Romance?

You "That would be Christian Slater"
by Jorseman December 19, 2011
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spanish main

The area of sea that stretched from the west coast of spain to its' latin american territories.
"Remember the Maine! To hell with Spain!"...apparentley
by Kung-Fu Jesus April 30, 2004
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Symmetra main

a Symmetra main is someone who will dump his dignity into the next trash can only to microwave you to the gates of hell. he shows absolutely no feelings of disgrace and shame and will declare that Symmetra is his "wife". there is no hope for returning to human after becoming a Symmetra main.
guy 1: have you seen that symmetra main?
guy 2: yeah I'm feeling like microwave lasagna now
by 9uvoufiywtwufou August 27, 2021
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maine muzzler

when you cum inside of a condom, then flip it in side out and slap a chick in the face with it
After I had sex with that chick, I showed her the maine muzzler.
by Jmills48 March 18, 2011
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mercy main

A kind, patient Overwatch player who has the most time on the hero Mercy. Not to be confused with a one trick Mercy, as those only have the capability to play mercy. DO NOT ASSUME ALL MERCY MAINS ARE ONE TRICKS. You will piss off a lot of Mercy mains by doing this. Mercy mains may only play Mercy because not enough players in Overwatch are willing to play support, or maybe they fall into support main and play other supports besides Mercy as well.
Player 1: Dude, I think badatgames is a one-trick mercy.
Player 2: Naw dude, they have 22 hours on Pharah. That's just a good mercy main.
by badatgames September 4, 2018
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main thing

As said in Post Malone’s 92 Explorer, main thing refers to a pussy.
“I hit your main thing twice
by Makayla Reese June 2, 2018
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Hanzo main

A sexy, smart and talented person with a huge D
"Yeah they're a real Hanzo main"
by Not_a_hanzo_main November 24, 2020
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