To give a girl's clit a real workout, I mean, like when you give it the rub-a-dub taking it between your thumb and index. Not to be confused with mere twiddle.
by Hugh G Rection October 07, 2003

To freak out while intoxicated.
by Vatrinna March 16, 2021

A kid who is shaking or just twitches all the time. Common name for kids who move with speed for a second or 2 for no reason at all. Mostly they call them "tweak" in high school. They just jolt for no reason.
by mike July 05, 2004

Tweak=ian look all around culver city marina del rey and santa monica so see it hit up all over the place
by tweak(ck17) May 27, 2003

–verb
1. To get very angry or randomly mad
2. To freak out
3. To yell
May also be seen as:
Tweak'ing
Tweak'er
Tweaking Balls
1. To get very angry or randomly mad
2. To freak out
3. To yell
May also be seen as:
Tweak'ing
Tweak'er
Tweaking Balls
by Tehbs. July 07, 2009

by Cacoo June 26, 2003

1. His guitar sounds like shit 'cause he's gotta tweak his amp.
2. When she heard me play my guitar she tweaked.
2. When she heard me play my guitar she tweaked.
by Buzz Cola October 23, 2003
