tweaker 

Someone who constantly worries about a situation and obsesses over the possible outcome of something before it happens. Someone who thinks a lot and dwells on things a lot.

I am worried about how my dress will fit, will he think I am fat?

Do you think I will get in to trouble? I am tweaking on the situation.

What will happen if the judge sends me to jail? I am a tweaker.

tweaker by kelsmaster August 9, 2009

Tweaker 

A word used popularly in Philadelphia, Pa to describe female dogs who get “smutted” around by a group of men. The men are either friends, cousins or even siblings maybe complete strangers but that's rare with Tweaks. Tweakers are often exposed on the Tweaker List page via Facebook. Tweakers are not aware that they’re tweakers, until they appear on the Tweaker List. However, 99.9% are still in denial after being featured on every list. You can always find a Tweaker on Broad & Olney, King of Prussia, and Franklin Mills. They're in there like swimwear.

Girl: I'm not a tweak, I'm 15 years old and I let 5 guys hit.
I only sucked 14 dicks this year. Yes, I'm on the tweaker page, but these girls just hating on me because I had sexual intercourse with their boyfriends.

Boy: Your the true definition of a tweaker.

Tweaker by Never Lying October 13, 2010

tweaker 

a person who has lost life. they say it can kill you the first time you try it...if it doesn't you will wish it had.

The most prettiest girl in school got caught up in tweak...she isnt so pretty now and she is really mean with big gashes in her face from picking at it and no eye brows cuz she must have got really bored and tweaked by herself...poor girl she will never be the same

tweaker by I dont care how they do it February 24, 2005

tweaker 

tweak=freak out, jumpy, on edge.

Shell tweaked when Mike scared her.

tweaker by ATXmoneymike January 26, 2005

Tweaker 

Philadelphia's (Philly's) own slut.
The word "tweaker" is often used to describe a girl with sloppy, slut-like attributes, and is known for getting with a lot of guys. A tweak is a nicer way of calling a female a whore, and or slut, and a tweaker may get with more popular, or famous guys. The word "tweak" is also used and is just a shorter version of the word "tweaker".

Malik: Yo, did you see Vanessa with Jamal last night? Yeah, she was giving him head in the back of the party, and everyone saw...
Kyle: Yeah, I know, that girl is such a tweaker.
Malik: Smh what a tweak.

Tweaker by Olive_Garden69 October 30, 2011

tweaker 

A small, long and narrow screwdriver, usually plastic, commonly used for adjustments to sensitive electronic components (coils, potentiometers etc)

"Hey Lou, pass me the tweaker, I need to make an adjustment here"

tweaker by anon-e-mouse April 11, 2005

Tweaker 

Tweaker: Boy/Girl tht go around fuckin everybody . Gettin passed around the whole team or city/place

Boy: there go tht tweaker over there
Girl: How She A Tweak
Boy: The Whole Team Was In Tht Bitch
Girl: Smh Fuckin Whore

Tweaker by TweeterTweet December 21, 2010