Tweaker

Someone using Crystal meth or ice are referred to as tweakers. They are commonly referred to as tweaking out as in a state of paranoia or moving and twitching profusely.
Look at the tweakers peeking out of the blinds.

Look ! That tweakers been down this aisle 17 times in 2 minutes.
by MizzuzKotzz×3 September 17, 2018
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Is That A Tweaker

A game residents of Terre Haute, Indiana play while driving through town. When you see someone you have to ask other people in the car, “Is that a tweaker?”. If you just guess yes, you are likely to be correct 75% of the time.
Turn on Locust Street, go a few blocks and when Donnie yells, “Is that a tweaker?” you’re in the right place.

What is that guy doing? Is that a tweaker?
by HairyGinger May 03, 2022
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tweaker

a tweaker is someone who has been doing Crystal Meth for a while and feens for it and is always twitching. Some one who is an addict for Meth.
L. - damn nigga YU're girl is a tweaker aint she?
P. - Ya im going to drop that bitch soon, she fucking up and be doing too much for the dopey
L. - oh, yah how much, give her my number in that case.
by baddxbxtchxdopey August 07, 2010
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tweaker

a female that is a whore or has multiple sex partners. Originated in Philly; used in Philly and parts of Delaware.
Jon-ayo she a tweaker. da whole crew hit dat!

or
Jay-yo why did u and yo girl break up? she was fine!
Jon-yeah she was fine but she was a tweaker
Jay-aw man!
by lilmamapullin April 02, 2010
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Tweaker

1. A person that's like a hoe

2. Some one who will talk to alot of females/males at once

3. Some one who's addicted to drugs
"Yo, you a tweaker for real"

"shut up tweaker!!"
by Philly Girl_14 June 20, 2009
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tweaker

1. A person who customizes an operating system, a.k.a. MS Windows or Linux.
2. A person who speeds up their computer. See also overclocker.
1. You know Ken, always changing his settings. Such a tweaker, really.
2. Hey, that Dave guy burned out his CPU again, tweaked it too much.
by Toba September 22, 2004
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tweaker

Someone who constantly worries about a situation and obsesses over the possible outcome of something before it happens. Someone who thinks a lot and dwells on things a lot.
I am worried about how my dress will fit, will he think I am fat?

Do you think I will get in to trouble? I am tweaking on the situation.

What will happen if the judge sends me to jail? I am a tweaker.
by kelsmaster August 10, 2009
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