Shortened version of the STD's ghonnorea, herpes, and syphilis. Usually refering to someone as being easy or dirty.
I'm pretty sure Joe has ghona-herpe-syphi-litis. That boy has been around the block more than a few times.
by KrazySkaterChick March 19, 2008
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A cocktail of various sexually transmitted diseases, only found in adolescent males. The crossing of these diseases can cause side affects such as slowed mental response, and a lack of penile girth or length. It is most commonly found in the Durham Co. club scene and has caused wide spread panic in the Winchester, England, area. Also one with the disease, can perform a party trick where one can put his or her (as a side affect can be an engorged clitoris) penis into a burette of de-ionised water, and causes the penis to disolve.
Mr. Wilson, I am sorry to tell you that you have contracted sypha-chla-herpe-aids.
by I'm not Lucca June 7, 2010
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What you tell your son or daughter before you know they are going to get a high on marijuana. Something you tell you boyfriend/girlfriend before you know they are going to smoke a blunt. Something you tell your friend before he hooks up with rando at the bar.
Hey johnny, don't go catchin herpes now.
Hey bri, be home by twelve, and don't go catchin herpes.

I know your cheating on me, but I still love you, but don't go catchin herpes.
by SsTtUu00 June 20, 2011
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A combination of herpes, hepatitis, and syphillis; the result of having sex with a nasty stripper
Man, that hoe from the titty-bar will give you herp-a-hep-a-syph-a-fuck-a-litis!
by SexyNelly July 19, 2006
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The opposite of Herp De Derp. Something you say to counter Herp De Derp.
Man - I just banged your mom
Woman - Herp de derp
Mom - Derp du herp.
by DerpMaster1234 November 22, 2011
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A person who has done something generally rude or mean.

A name used in a situation where you are telling someone off in the meanest way possible.
by ATL ROX! May 15, 2011
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A mass of STD's that can only occur in someone that has done an entire poke'dex full of people they don't know that could have STD's
How does someone who has had sex with over 400 people not end up with Super-Herpe-gono-aid's-ymidiae?!?!?!
by Fangbreaker April 29, 2012
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