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Slav speedball 

The state you are in after snorting a line of blow and ripping a bong.
- He died from speedball!
- Have you heard of slav speedball?
- No, how does it compare?
- It's not as deadly and soul-crushing but it's a lighter version of an inhibiting, 'downer' drug and a hardcore accelerating stimulant - blow and weed.
Slav speedball by matopato July 11, 2021

Speedball 

A speedball is NOT heroin mixed with cocaine. Speedballs don't contain cocaine or Crack. A speedball is heroin mixed with speed (Amphetamine, Ethylamphetamine). It's in the name, stupid. Speed is the Speed part and Heroin is the Ball part. Heroin makes you sleepy and Amphetamine makes you awake and energetic. Don't do heroin! Stick to Kratom! Also, don't do fentanyl. You can dissolve Amphetamine and Heroin in DMSO and put it on your skin and it goes right inside your body. The speedball can kill, but if you survive, you can get super high.
I mixed Heroin and Amphetamine in DMSO and poured it on my skin. It ended up in my bloodstream and I got super high. This is a great speedball.
Speedball by CognitiveFuel January 12, 2023

pigeon speedball

A mixer of Neurosleep and pre-workout designed for those abstaining from drugs and alcohol.
Get that missionary a pigeon speedball, we will go HAM.

Frisco Speedball 

a mixture of cocaine, heroin, and LSD. a variation on the classic speedball, which is simply a mixture of cocaine and heroin for intravenous injection. taken from the idea that LSD was first widely popular in the Haight-Ashbury section of San Francisco in the 1960's.
I really don't think anybody does Frisco Speedballs anymore, and that's just sad.
Frisco Speedball by mcGherk July 30, 2006

Sleezeball 

Nicholas Duffy, a person with no ethics, no character. A person who lies and cheats to benifit themselves, a dishonest person.
Nicholas duffy what a sleezeball!
Sleezeball by Moss333 June 6, 2019

Yuppie speedball 

Two beers and a coffee - typically consumed by yuppies at lunch on a workday.
"It's Dog-fucking Friday, let's go do a few yuppie speedballs."
Yuppie speedball by Cockulon 3000 February 24, 2005