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1. depression, melancholy

2. a style of jazz music
If you have the blues, eat a square of chocolate.
blues by The Return of Light Joker January 13, 2009
Slang word for oxycodone 30 mg.
Hey man , you know anyone holding blues?
Blues by Mr-No-giggles October 20, 2017
Trini slang for porn.
They catch him watching blues in the school bathroom. He get suspended eh bai.
Blues by TriniJedi December 18, 2019
A Percocet pill found on the streets. Typically they are counterfeit versions that have been laced with fentanyl, a synthetic opioid said to be 100 times stronger than morphine. These pills are easier to produce than heroin so it’s getting more common to find them and get them for cheaper on the black market.
“Fuck I’m starting to get dope sick... you know where to find any blues??”

“Yo did you hear homie OD’d yesterday? Apparently he got into some blues that were laced with carfentanil. That shits powerful.”
Blues by ⚛ZoDro⚛ February 6, 2021
AZ slang for Mexican perc 30s with fentanyl
Dude ever since I've been doing blues, I hardly shoot up at all! Half my friends are dead from em but who's counting.
blues by nrrs July 10, 2021
Its a Mexican oxy or a fake oxycodone that is a blue clandestine fentynal pill with a letter m on one side and a 30 on the other
Yo can I snag a couple blues from you I'm sick as hell
Blues by Mr. Murk September 9, 2021