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Ed Zachary Disease

When someone's face looks Ed Zachary like their ass.
Once, an ugly girl that was making a pass at me described that she wasn't feeling very well.
I said, "Well, if I were a doctor, I think I might diagnose you with Ed Zachary Disease."
She asked what it was and I said, "When your face look Ed Zachary like yo ass."
She wasn't amused.
by Roy L'Ourtiere September 7, 2008
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Sexually Transmitted Disease

a disease or illness passed through sexual intercourse, exchange of bodily fluids. one partner must have the condition to pass it on. sex, oral sex, anal sex, kissing, or any type of touch from open area to open area can connect to abstract one. more commonly known as an STD
Ben passed on AIDS which is an Sexually transmitted disease.
by Siddalee February 7, 2003
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Facebook Disease (FBD)

When your profile picture doesn't look like you, but it looks worse than what you look like in real life. (Can also apply to myspace, but particularly facebook)
Guy:Have you seen my profile pic???
Girl:OMG its horrible. You have a serious case of Facebook Disease (FBD). You look way better in person.
Guy: Oh really? Thanks.
by Dough.Boy. June 14, 2008
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Markinsons Disease

Noun: A disease similar to Parkinsons, named after Mark G, from Westcliff in Essex. The disease is characterised by boughts of idiocy; an inability to focus; clumsiness; things breaking from the other side of the room; not knowing when it's your turn in Risk. Potentially fatal if not treated.

Often found in combination with Markolepsy after consumption of Markotics
"Mark!!! Mark!!! It's your turn, fool. Go and sort your Markinsons Disease out!"
by Michael A A February 7, 2008
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asshole reflux disease

asshole reflux disease - the heartburn, or acid reflux, a person gets when an asshole, usually one who has some superiority of position, enters a room
Marie gets a nasty taste of acid in her mouth from asshole reflux disease whenever Phylis walks in.
by TooSick4U October 6, 2008
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Alzhumor's Disease

Alzheimer's Disease + humor.

A condition of older people that prevents them from seeing the humor in things that younger people find hilarious.
Uncle George left the room when we put in the "Office Space" DVD. I think he's got Alzhumor's Disease.
by PieterB July 30, 2010
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old timer's disease

The elderly are not necessarily the only victims of old timer's disease, although they are the ones who get it the most.
by The Return of Light Joker June 13, 2010
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