Used to state that you do not care about the other person's excuse, no matter how serious it is.
Student: But sir, I was held up because I was giving mouth-to-mouth to someone who had cardiac arrest.

Teacher: I don't care if you're talking to God, detention!
by Shadowassasin13 December 16, 2010
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This phrase is tagged to the end of one's speech in order to reveal an innuendo or undertone. It is expressed with a wide-eyed expression and a tone of confusion. It is often synonymous with "That's what she said".

Unlike "That's what she said", it is proper for one to add this phrase to the end of his/her own speech, as well as for others to do the honor for him/her.
Scott: "This female's pelvis has been articulated... I don't even know what that means"
by Carriacou Archaeology 2008 August 02, 2008
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Combining a reference to two and a half men and the fact that you care so little about what the other person's saying.
-Hey, guess what I was doing last night?
-You know what? I don't give two and a half shits!
by Deathgleaner May 24, 2010
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What one might say when another person makes you slightly(or considerably) annoyed.
You are standing in line and a lady screams at you to move to the back for her fair turn.

You reply with, "Bitch, I don't know your life!" and casually move to the back of the line.
by Lalaleah December 15, 2008
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I don't give a fuck g

A common exchange between a negro and a gangbanger. Often used needlessly.
Gangbanger:Bob Saget smokes-ah-da reefer.
NegroI don't give a fuck g. 3827508912365-384165-3465-83641-9581634-586312-4856-3140531465-=314256=13425

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by lazirus July 06, 2004
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I don't have many fucks left

I don't have many fucks left is When you really are on ur last nerve before SOMEONE SETS U TO THE DEEP END
I'm really starting to get to the point where I don't have many fucks left to give anymore because you're taking advantage of our friendship
by Faithmoriahfaith October 06, 2018
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