To give up on something; To not care or be bothered about/with something/someone.  Another way of saying "screw this".
by Little Hands April 15, 2009
 Get the stuff itmug.
Get the stuff itmug. A word that is a proper subsitute for any other word.  Present most often in one sided conversations, or when a conversation is running dry,the random insertion of "stuff" breaks the silence for as long as it takes to say the word.
A: Whacha been up to?
B: Eh, stuff.
A: Do anything cool this weekend?
B: Did some stuff.
A: Buy anything?
B: ...stuff.
B: Eh, stuff.
A: Do anything cool this weekend?
B: Did some stuff.
A: Buy anything?
B: ...stuff.
by Lunatic Star November 24, 2003
 Get the stuffmug.
Get the stuffmug. He was such an egotistical Nietzschean surfboy that he had to go stuff that Croatian girl. And then go off and tell everyone: "Dude, I stuffed her!"
by girl24 December 11, 2006
 Get the stuffmug.
Get the stuffmug. everything you can think of
wow that girl has nice stuff
id like some of that stuff
whoa! you see that stuff last night?
i just stepped in some stuff
id like some of that stuff
whoa! you see that stuff last night?
i just stepped in some stuff
by lioliadis, josh(enms) east northport new york(dont May 20, 2003
 Get the stuffmug.
Get the stuffmug. a japanese way of describing a plural of ' stuff '.   however, stuff is already plural, but it being a plural noun, if there are more than one item as part of ' stuff ' , then people will add an s. 
my japanese friend taka explained this to me.
my japanese friend taka explained this to me.
by mattback February 24, 2004
 Get the stuffsmug.
Get the stuffsmug. by random guy June 7, 2004
 Get the the stuffmug.
Get the the stuffmug. 